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Head of Discovery

  • Full Time
  • Chicago


Location: Chicago

Pre-series A biotech based in the US looking for a Head of Discovery. The company are focused on innovative drug discovery and development with a collaborative and entrepreneurial culture, offering a dynamic work environment where talented individuals can make a significant impact.

This is a hybrid position.

Position Overview:

We are seeking a highly motivated and experienced Head of Discovery to lead research and development efforts. In this key leadership role, you will be responsible for overseeing and driving the discovery of novel therapies. Managing a team of talented scientists, and collaborating with cross-functional stakeholders to advance the pipeline. The successful candidate will have a deep understanding of drug discovery processes, a strong track record of successful project management, and the ability to thrive in a fast-paced and dynamic environment.

Responsibilities:v Head of Discovery

  1. Lead and manage the discovery team, providing guidance, mentorship, and fostering a collaborative work environment.
  2. Drive the strategic direction and execution of drug discovery programs to meet project goals and timelines.
  3. Utilize your expertise in target identification, hit identification, lead optimization, and preclinical candidate selection to advance our portfolio.
  4. Develop and implement innovative strategies and technologies to accelerate the drug discovery process.
  5. Collaborate with cross-functional teams including medicinal chemistry, biology, pharmacology, and translational sciences to drive integrated drug discovery efforts.
  6. Stay abreast of the latest scientific advancements and industry trends in drug discovery, evaluating new opportunities and technologies to enhance our capabilities.
  7. Build and maintain relationships with external partners, including academic institutions, CROs, and other biotech/pharmaceutical companies, to leverage their expertise and resources.
  8. Effectively communicate project updates, progress, and data to senior management, presenting scientific findings and recommendations.
  9. Ensure compliance with all applicable regulatory guidelines and industry best practices throughout the drug discovery process.
  10. Contribute to the development and implementation of standard operating procedures (SOPs) and quality control processes to ensure robust and reproducible results.
  11. Development of new lab spaces, including the addition of new technologies and equipment, and implementation for lab work.

Qualifications: Head of Discovery

  1. Ph.D. in a relevant scientific discipline (e.g., Immunology) with a minimum of 8 years of industry experience in drug discovery for autoimmune diseases.
  2. Proven track record of leading successful drug discovery programs from target identification to candidate selection.
  3. Strong leadership and management skills, with the ability to motivate and inspire a team to achieve goals.
  4. In-depth knowledge of drug discovery processes and methodologies, including hit identification, lead optimization, and preclinical development.
  5. Experience with a wide range of drug target classes and therapeutic areas, with a focus on small molecules.
  6. Excellent problem-solving and decision-making abilities, with a proactive and results-oriented mindset.
  7. Exceptional communication skills, both written and verbal, with the ability to present complex scientific concepts to diverse audiences.
  8. Strong project management skills, including the ability to prioritize and manage multiple projects simultaneously.
  9. Knowledge of regulatory requirements and industry standards in drug discovery.

We offer a competitive salary, comprehensive benefits package. If you are passionate about driving innovation in biotech and making a meaningful impact in patients’ lives, we would love to hear from you.

To apply, please submit your CV and a cover letter outlining your relevant experience and why you are interested in joining our team.


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